How to Use in silico in a Sentence

in silico

adverb or adjective
  • Levy’s book about the science and nuance of life creation in silico.
    — New York Times, 13 Mar. 2020
  • Rather than putting that on the page, Codemasters used it to describe each car in silico.
    — Jonathan M. Gitlin, Ars Technica, 17 Aug. 2018
  • The in silico movement for drug discovery is in its nascence, but researchers like Shoichet have advanced the field over the past four years.
    — Meghana Keshavan, STAT, 1 Oct. 2022
  • And the consequences when controlling a real jet fighter can be a lot more severe than just testing in silico.
    — Eric Berger, Ars Technica, 19 Apr. 2024
  • To be clear, Lake and his colleagues do not claim to have replicated in silico how toddlers actually learn.
    — Sarah Zhang, The Atlantic, 5 Apr. 2024
  • Because the area of science is machine learning, the experiments take place entirely in silico.
    — The Physics Arxiv Blog, Discover Magazine, 13 Sep. 2024
  • But not everyone is confident about the applications of in silico testing.
    — Arvind Dilawar, Newsweek, 12 Oct. 2017
  • Finkbeiner and his team call their machine-learning approach in silico labeling, or ISL for short.
    — Robbie Gonzalez, WIRED, 12 Apr. 2018
  • For all its apparent power, in silico work will not replace in vitro testing — and certainly not clinical trials.
    — Quanta Magazine, 9 Mar. 2020
  • How to best use that space is something Airbus is also exploring, although that's being done full size and in silico rather than with action figures and a scale model.
    — Jonathan M. Gitlin, Ars Technica, 11 Feb. 2020
  • Afterward, Toyota engineers were able to reconstruct the event in silico, then re-enact it on a test track using cars equipped with Guardian.
    — IEEE Spectrum, 7 Jan. 2019
  • But that hasn't stopped our friends at CXC Simulations from having a go at reverse-engineering things in silico.
    — Jonathan M. Gitlin, Ars Technica, 13 Jan. 2020
  • The agency agreed that such in silico simulations were sufficient for regulatory approval of inpatient human trials.
    — Boris Kovatchev, IEEE Spectrum, 21 Nov. 2021
  • Wylie was fascinated by the concept of reconstructing a society in silico—capturing people’s data trails and their behavior to remake the actual world.
    — Wired, 15 Oct. 2019
  • His lab combines a machine learning platform that generates new molecules in silico with a synthesizer that prints out these new molecules for a pipetting robot, which then performs experiments on them.
    — Quanta Magazine, 9 Mar. 2020
  • Regulators must invest in a portfolio of programs that move beyond in silico testing to support use of AI in real, diverse clinical environments.
    — Mark P. Sendak, STAT, 7 Feb. 2024
  • Beyond speeding results and mitigating the risks of clinical trials, in silico medicine can be used in place of risky interventions that are required for diagnosing or planning treatment of certain medical conditions.
    — Daniel E. Hurtado, Scientific American, 10 Nov. 2020
  • Biotech entrepreneurs now routinely utilize in silico modeling and contract research organizations to conduct early-stage experiments.
    — Neil Littman, Forbes, 16 June 2021
  • One of the key transformations is the fundamental shift in which companies are using AI and machine learning technologies to model and test potential drugs in silico prior to validating them in wet labs.
    — Sage Lazzaro, Fortune, 14 Dec. 2023
  • Millions of p-JAMs are burned every time a single supercomputer simulates, say, a drug molecule’s interaction with biological cells in silico, rather than in humans.
    — Mark P. Mills, National Review, 20 Sep. 2019
  • By integrating real-time clinical data with longitudinal biology, digital twins allow researchers and clinicians to test hypotheses in silico before committing to costly and risky clinical trials.
    — Niven R. Narain, Forbes.com, 18 Sep. 2025

Some of these examples are programmatically compiled from various online sources to illustrate current usage of the word 'in silico.' Any opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback about these examples.

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